• Memory impairment and one or more of:
— aphasia
— apraxia
— agnosia
— disturbance in executive functioning (ie, planning,
organising, sequencing, abstracting).
• These cognitive changes are sufficient to cause significant
impairment in social or occupational functioning and
represent a significant decline from a previous level of
functioning.
• These changes are not due solely to delirium or other
neurological conditions (eg, cerebrovascular disease) or
systemic conditions (eg, neurosyphilis).
• The course is characterised by gradual onset and continuing
decline.
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